Lihlahisoa
6-Methyluracil 2,4-Dihydroxy-6-methylpyrimidine
Li-synonyms: 6-methyluracil; 6-methyluracil, 14C-e ngotsoeng; AWD 23-15; AWD-23-15; methacil; methyluracil; pseudothymine
Thepa ea lik'hemik'hale ea 6-Methyluracil
● Ponahalo/Mmala: bosoeu ho isa ho bosoeu ba kristale bo tiileng
● Khatello ea Mouoane: 1.16E-07mmHg ho 25°C
● Sebaka se qhibilihang:318 °C (dec.)(lit.)
● Refractive Index: 1,489
● Sebaka se Belang: 420.4 °C ho 760 mmHg
● PKA:pK1:9.52 (25°C)
● Ntlha ea Flash:208 °C
● PSA: 65.72000
● Boima ba 'mele: 1.226 g/cm3
● LogP: -0.62840
● Mocheso oa ho Boloka.: Sepakapaka se sa keneleng, Mocheso oa Kamore
● Solubility.:DMSO (Hanyenyane), Methanol (Hanyenyane, E futhumetse, e Sonicated)
● Ho qhibiliha ha Metsi.:7 g/L (22 ºC)
● XLogP3:-0.8
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Accepter Palo:2
● Rotatable Bond Count:0
● Hantle 'Misa: 126.042927438
● Palo ea Athomo e Boima:9
● Ho rarahana:195
Bohloeki/ Boleng
99% * data ho tsoa ho barekisi ba sa sebetseng
6-Methyluracil * data ho tsoa ho barekisi ba reagent
Boitsebiso bo Boreleli
● Litšoantšo:
Xn
● Likhoutu tsa Kotsi:Xn
● Lipolelo: 62-63
● Lipolelo tsa Tšireletseho: 36/37/39-45-36/37
Lifaele tsa MSDS
E molemo
● Lipososelo tsa Canonical: CC1=CC(=O)NC(=O)N1
● Litšebeliso: 6-Methyluracil (cas# 626-48-2) ke motsoako o sebetsang ho organic synthesis.6-Methyluracil, e tsejoang hape e le thymine kapa 5-methyluracil, ke motsoako o nang le motsoako oa lik'hemik'hale C5H6N2O2.Ke motsoako oa pyrimidine le karolo ea nucleic acid.Thymine, hammoho le adenine, cytosine, le guanine, ke e 'ngoe ea li-nucleobases tse' nè tse fumanoang ho DNA. Thymine e phetha karolo ea bohlokoa ho DNA ka ho kopana le adenine ka hydrogen bonding, ho etsa e 'ngoe ea lipara tsa motheo tse etsang sebopeho sa double helix.Ka ho khetheha, thymine e theha likamano tse peli tsa hydrogen le adenine ho DNA.Ho RNA, uracil e nkela thymine sebaka hape e etsa lipara tsa motheo le adenine.Thymine e ikarabella ho jara tlhahisoleseding ea liphatsa tsa lefutso ka har'a molek'hule ea DNA.E sebetsa e le moralo oa ho qaptjoa ha liprotheine 'me e phetha karolo ea bohlokoa ho fetiseng litšobotsi tsa liphatsa tsa lefutso ho tloha molokong o mong ho ea ho o mong.Ka ntle ho karolo ea eona ho DNA le RNA, thymine e boetse e sebetsa e le sepheo sa bohlokoa ho lithethefatsi tsa anticancer.Li-chemotherapeutic agents li lebisa tlhokomelo ho li-enzyme tse ikarabellang bakeng sa ho kopanya thymine, kahoo li thibela ho hōla ha lisele tsa kankere.Ha u sebetsana le thymine, ke habohlokoa ho latela mekhoa e nepahetseng ea ts'ireletso ea laboratori, ho kenyeletsa ho apara lisebelisoa tse loketseng tsa tšireletso le ho sebetsa sebakeng se nang le moea o motle.Ho phaella moo, thymine e lokela ho bolokoa sebakeng se omileng le se pholileng ho thibela ho senyeha le ho boloka botsitso ba eona.
